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  • Products → Microbiome → OMNIgene•XTRACT ULTRA | OM-XTU-50

    Extract high-quality DNA and RNA from a wide range of microbiome sample types

    Optimized sample-specific extractions to recover large quantities of microbial DNA and RNA

    OMNIgene™•XTRACT ULTRA | OM-XTU-50

    OMNIgene™•XTRACT ULTRA OM-XTU-50 product kit

    Extract total nucleic acids from a wide range of microbiome samples with optimized protocols that improve efficiency and minimize environmental impact

    The OMNIgene™•XTRACT ULTRA kit recovers DNA and RNA from high biomass samples, such as fecal, and low biomass samples, such as skin. The modularity of the OMNIgene™ extraction technology enables it to support most sample types while providing input volume flexibility that allows the user to tailor the extraction protocol based on sample biomass and downstream research assay requirements.

    Technological improvements enable OMNIgene™ extraction kits to provide unparalleled performance with inhibitor-rich stool samples and difficult low biomass samples, improving yields and analyte quality compared to currently available extraction kits. OMNIgene™ extraction kits are validated for a wide range of sample types (stool, oral, vaginal, and skin) and are fully optimized for samples collected and preserved in OMNIgene™ devices*.

    Additionally, the OMNIgene™ extraction technology does not contain or require the use of hazardous chemicals such as guanidinium salts or phenol-chloroform, increasing user safety and minimizing the generation of chemical waste.

    Extract total nucleic acids from diverse microbiome samples with optimized protocols

    Optimized sample-specific protocols

    Maximize research outputs with superior yields and high-quality analytes.

    Safety

    For a safer working environment, avoid using harsh chemicals, such as guanidinium, phenol or chloroform.

    Minimal environmental impact

    Environmentally friendly workflow developed to minimize plastic waste.

    Improved efficiency

    Reduced extraction times through optimized protocol steps, compared with other extraction kits.

    Recover large quantities of DNA and RNA from a variety of microbiome samples with the OMNIgene™•XTRACT ULTRA kit

    OMNIgene™•XTRACT ULTRA average yields (min.–max.)
    Sample type Recommended input volume into extraction DNA RNA
    Skin (cheek) 1 mL 79.8 ng (16.6 ng–159.0 ng) 61.0 ng (12.5 ng–149.6 ng)
    Skin (forearm) 1 mL 11.1 ng (5.9 ng–20.9 ng) 4.3 ng (1.8 ng–8.1 ng)
    Saliva 500 µL 7.4 µg (0.4 µg–23.3 µg) 0.3 µg (0.1 µg–0.6 µg)
    Vaginal 500 µL 15.1 µg (6.9 µg–29.9 µg) 1.2 µg (0.5 µg–2.3 µg)
    Fecal 250 µL 7.9 µg (3.3 µg–12.4 µg) 1.3 µg (1.0 µg–2.5 µg)

    Kit contents and attributes

    OMNIgene™•XTRACT ULTRA | OM-XTU-50

    Number of extractions per kit
    50
    Optimized protocols for a wide range of sample types, including skin, vaginal, oral and fecal
    ✔
    Efficient recovery of high-quality DNA and RNA
    ✔
    Reduced extraction time compared with other methods
    ✔
    Avoids the use of harsh chemicals
    ✔
    Effective inhibitor removal
    ✔

    Literature

    Data Sheets

    OMNIgene™•XTRACT ULTRA | OM-XTU-50 Datasheet

    Safety Data Sheets

    OMNIgene™•XTRACT ULTRA | OM-XTU-50 MSDS

    Handbook

    OMNIgene™•XTRACT ULTRA | OM-XTU-50 Handbook

    White Papers

    OMNIgene™•XTRACT | OM-XT-50 White Paper -- Coming Soon

    Scientific Posters

    Microbes In Women's Health 2025 Poster

    Designing a universal microbiome extraction solution for low- and high-biomass samples collected in DNA Genotek devices. 2025 Poster

    Microbiome collection devices

    The OMNIgene™ line of products also includes all-in-one systems for quantitative profile analysis pf the gut and vaginal microbiome.

    View all microbiome collection devices

    OMNIgene™•XTRACT

    Recover large quantities of high-quality microbial DNA and RNA from difficult sample types with optimized sample-specific extractions

    OMNIgene™•XTRACT | OM-XT-50

    *For Research Use Only. Not for diagnostic purposes.

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    DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc. (NASDAQ: OSUR), focuses on providing high-quality biological sample collection products and end-to-end services for human genomics, microbiome and infectious disease applications. The Company's Oragene•Dx and ORAcollect•Dx product lines are the first and only FDA 510(k) cleared saliva-based DNA collection devices for in vitro diagnostic use. DNA Genotek also offers Research Use Only products to collect and preserve large amounts of DNA or RNA from multiple sample types. DNA Genotek markets its products worldwide and has a global customer base with thousands of customers in over 100 countries.

    © 2025 DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc., all rights reserved.

  • Industry Solutions
    • Human Genomics - Academic Research
    • Human Genomics - Clinical Diagnostics
    • Microbiome - Academic Research
    • Clinical Microbiome
    • Infectious Disease
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    • Animal
    • H L A Typing
  • Products
    • Human Genomics
      • All research DNA & RNA collection kits (saliva)
      • Total Nucleic Acids (Host & Microbial)
        • NEW OMNIgene•SALIVA | OMR-610
      • DNA Extraction Reagents
        • prepIT•L2P | PT-L2P (saliva)
        • prepIT•Q2A | PT-Q2A (saliva)
    • Microbiome & Metabolomics
      • All Microbiome & Metabolomics Collection kits
      • Microbiome
        • Oral
          • OMNIgene•ORAL | OM-501 (saliva)
          • OMNIgene•ORAL | OME-505 (saliva)
          • OMNIgene•ORAL | OMR-110 (gum/plaque)
          • OMNIgene•ORAL | OMR-120 (tongue)
        • Skin
          • OMNIgene•SKIN | OMR-140
        • Vaginal
          • OMNIgene•VAGINAL | OMR-130
        • Gut
          • OMNIgene•GUT | OM-200 (feces)
          • OMNIgene•GUT | MP-017
          • OMNIgene•GUT | DNA & RNA | OMR-205
        • Total Nucleic Acids (Host & Microbial)
          • OMNIgene•SALIVA | OMR-610
        • Anaerobe Culture and Media
          • BIOME-Preserve Microbiome Collection Kit
          • Agar Plates
          • Broth Media
          • PRAS Dilution blanks
        • NEWExtraction
          • OMNIgene•XTRACT | OM-XT-50
          • OMNIgene•XTRACT ULTRA | OM-XTU-50
      • Metabolomics
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          • OMNImet•GUT | ME-200
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