Molecules, microbes and multiomics is DNA Genotek’s podcast * all about the changing landscape of genomics, microbiome and the evolution to multiomics. In each episode, we explore a topic related to one of these scientific fields and give you expert advice and commentary that can help both researchers and clinicians with their projects including critical elements such as DNA and RNA sample collection and analysis of those samples to provide optimal data. We hope you join us as we explore what it takes to drive innovation and produce tangible benefits with your projects.
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September 01, 2023 ● Ep.28
Breaking new ground in PTSD research: Insights from The Consortium for Post-Traumatic Stress Disorders
In this episode, Ajin Abraham (Strategic Marketing Manager, Genomics) and Sanna Abbasi, Ph.D. (Scientific Writer/Content Specialist) interview a group of leaders ... in the Psychiatric Genomics Consortium for Post-Traumatic Stress Disorders (PGC-PTSD). The purpose of the Psychiatric Genomics Consortium is to unite investigators around the world to conduct meta- and mega-analyses of genome-wide data for psychiatric disorders. We talk about the mission of the PGC-PTSD workgroup, how genomics is contributing to discoveries and advancing the field, the impact of advocacy on policy, and the benefits of using saliva for investigation. see more
May 23, 2023 ● Ep.27
Expand into multi-omics: DNA Genotek and Diversigen 2021 grant program winner
In this podcast, we interview Dr. Jonas Schluter, Assistant Professor from the Department of Microbiology at the Grossman School of Medicine at NYU Langone Health ... and a winner of the DNA Genotek and Diversigen 2021 Expand into Multi-omics grant, discuss his research. see more
November 04, 2021 ● Ep.26
Phosphorus: Stretching the Capabilities of Clinical-Grade Genetic Testing
We invited Alexander Bisignano, CEO of Phosphorus, to tell us more about his company’s application of genetic testing ... and to share what is in store for them in the future. see more
August 20, 2021 ● Ep.25
Forensic science and the oral microbiome
Can the oral microbiome help law enforcement link suspects to crime scenes or evidence? In this episode of Molecules, Microbes and ... Multiomics Heloise Breton PhD, a product manager at DNA Genotek with a background in forensic science, and Megan Anderson, a recent graduate from Rock Canyon High School, chatted with us about Megan’s project on the oral microbiome in collaboration with the team of scientists at Diversigen. see more
April 21, 2021 ● Ep.24
Urine the 'golden sample': Why is urine so exciting in cervical cancer prevention?
We recently had the opportunity to interview Dr. Severien Van Keer, a post-doc researcher at the VAXINFECTIO research group, ... at the University of Antwerp. Her research primarily focuses on Human Papillomavirus (HPV) detection in first-void urine, and the potential of urine as a sample type for cervical cancer screening. Her research also includes Novosanis' Colli-Pee®, a first-void urine collection device. see more
April 15, 2021 ● Ep.23
Oral microbiome: The key to better therapeutics
An interview with Dr. Brian Klein, co-founder of Brick Built Therapeutics. One new start-up microbiology company, Brick Built, ... is focused on the potential of the human oral microbiome. Our two microbiome product managers at DNA Genotek, Dr. Heloise Breton, and Laura Cunningham, had the pleasure of speaking with Brick Built Therapeutics co-founder Dr. Brian Klein about the role and future potentials of the oral microbiome in our health and biotech industry. see more
Feb 18, 2021 ● Ep.22
Leaving no microbe behind: Shoreline Biome’s easy solutions for microbiome NGS
Shoreline Biome is a microbiome-focused company that provides simple solutions for microbiome next-generation sequencing. ... They develop tools and reagents to support end-to-end microbiome analysis. We talk about the amazing work of the team at Shoreline Biome and had the pleasure to interview their Director of R&D, Dawn Gratalo. see more
Feb 09, 2021 ● Ep.21
Behind the data: an interview with Dr. Dan Knights
In this interview with Dr. Dan Knights, Senior Scientific Advisor of Diversigen, learn about the future of data generation from microbiome samples. ... Dr. Knights discusses how he started in microbiome and bioinformatics research, ways to increase the power of microbiome studies, and different signals within the microbiome. see more
Jan 07, 2021 ● Ep.20
RNA breakthroughs in autism, concussions, and COVID-19
In this podcast, we explore how DNA Genotek and Quadrant Biosciences have been working together to support advancements in various diseases ... via RNA research and collection.Together, they've created RNA tests for early detection of autism spectrum disorder, Parkinson’s disease, traumatic brain injury, and COVID-19. see more
Dec 16, 2020 ● Ep.19
Probiotics, a possible solution to COVID-19 transmission?
We interview a team from Duke University in Durham, North Carolina, who are exploring the impact of probiotics in COVID-19 transmission with a ... new clinical trial: Probiotics To Eliminate COVID-19 Transmission in Exposed Household Contacts (PROTECT-EHC). see more
Nov 12, 2020 ● Ep.18
Personalized skin care: the beauty industry diving into the microbiome
The interest in human microbiome has widened from the gut to other parts of the human body, like skin. One company saw an opportunity to ... combine the science of the human skin microbiome, makeup and skincare. In this episode of Molecules, Microbes, and Multiomics, we interview the co-founders of Pure Culture Beauty Joy Chen, former CEO of Yes To and H2O+ Beauty, and Victor Casale, former chief chemist of MAC Cosmetics and co-founder of Cover FX. see more
Oct 27, 2020 ● Ep.17
Challenges and solutions for global shortages of materials for COVID-19 testing
When the pandemic hit, the demand for COVID-19 testing drastically increased, resulting in shortages of COVID-19 sampling and laboratory ... supplies and impacting the number of tests that could be performed. When we confirmed that our collection devices could stabilize, and inactivate the SARS-CoV-2 virus, we knew we could help. In this podcast we discuss the challenges and solutions for global shortages of materials for COVID-19 testing featuring DNA Genotek's COVID-19 experts. see more
Oct 21, 2020 ● Ep.16
Urine as a game-changing liquid biopsy in cancer biomarker detection
We recently had the opportunity to interview Professor Patrick Pauwels, head of the laboratory of molecular pathology and co-director ... of CORE, a joint oncology research platform with the University of Antwerp. This podcast discusses the potential of liquid biopsies, such as urine in the field of cancer research especially when tissue is an issue. It also highlights URODETECT, a collaborative project between CORE and Novosanis, which focuses on investigating urinary biomarkers for prostate and breast cancer using the Colli-Pee® device. see more
Aug 28, 2020 ● Ep.15
Metabolomics and the microbiome
The question of “What is Metabolomics” has been buzzing around the scientific community. With the advances of new technology, a gateway to ... studying metabolomics has been opened. Over recent years, microbiome researchers have begun to incorporate metabolomics, the “missing piece of the puzzle”, as part of their multiomics studies. To understand that missing piece more clearly and what it could mean for the future of multiomics, we feature two experts from DNA Genotek, Dr. Heloise Breton, Product Manager for Microbiome products, and Dr. Olle de Bruin, R&D Scientist - microbiome/metabolomics. see more
Aug 13, 2020 ● Ep.14
Solving the mysteries of your pet’s gut health
Nom Nom is not your average pet food company. In addition to delivering fresh, healthy meals for cats and dogs created by a ... team of veterinary nutritionists,they use gut microbiome samples submitted by their customers to study the link between nutrition and pet health. Nom Nom partners with Diversigen to analyze these samples and provide the accurate sequencing and bioinformatics analysis the Nom Nom scientists require to learn about the impact of nutrition on pet health. We speak with Dr. Ryan Honaker, the director of Microbiology at Nom Nom, in the latest episode of our Molecules, Microbes, and Multiomics Podcast. see more
June 17, 2020 ● Ep.13
Detection and full genotyping of Human Papillomavirus (HPV) in first-void urine
We recently had the opportunity to interview Rebecca Millecamps, a Marketing Manager at Fujirebio, a global leader in the field of ... in vitro diagnostics diagnostics (IVD). In 2019, Novosanis and Fujirebio, signed a worldwide, non-exclusive agreement for the distribution of Colli-Pee®, Novosanis’ urine collection device for use with Fujirebio’s INNO-LiPA HPV genotyping Extra II assay. This partnership enables detection and full genotyping of Human Papillomavirus (HPV) in first-void urine (first 20 mL of urine) collected with Colli-Pee®. In this podcast, Rebecca discusses how urine testing will impact HPV testing, what the benefits are of performing HPV genotyping in urine samples and the future for urine testing for HPV compared to cervical samples. see more
Mar 27, 2020 ● Ep.12
How to ensure the best sequencing results from saliva and fecal samples
DNA Genotek has expertise with many different non-invasive sample types including saliva for genomic and feces for microbiome analysis. ... With any sample type, quality is paramount to generate the best sequencing results and subsequently to produce the most accurate data. In this podcast, Mike Tayeb and Brice LeFrancois, two experts from our research and development team highlight the best practices they use in the lab with saliva and fecal samples to get optimal sequencing results. see more
Feb 25, 2020 ● Ep.11
SPARK project provides evidence for autism risk genes
This episode of Molecules, microbes and multiomics features an interview with Pamela Feliciano, Ph.D. who is the Scientific Director for SPARK ... (Simons Foundation Powering Autism Research through Knowledge). Launched in 2016, SPARK is designed to speed up research and advance our understanding of autism. SPARK, the largest study of autism ever, aims to make important progress possible. Learn about their project and why they use DNA saliva collection as their method of choice. see more
Feb 13, 2020 ● Ep.10
Industry leaders come together to support microbiome discovery
UPDATE: On May 12, 2020, CoreBiome rebranded as Diversigen Inc. As the microbiome industry grows and evolves, so has our team of microbiome ... experts. In 2019, DNA Genotek’s parent company, OraSure, acquired both CoreBiome and Diversigen. Through these acquisitions, we gained Diversigen's industry recognized CLIA/CAP state-of-the-art techniques with expert consultative microbiome services, and the strength of CoreBiome's innovative scalable sequencing technology. In this podcast, Lisa Gamwell, Services Product Manager at DNA Genotek speaks with Dan Knights, CEO of CoreBiome and Joy Nassif, Chief Operating Officer at Diversigen, to discuss their companies and how these teams will to work together to help advance the microbiome industry as a whole. see more
Dec 11, 2019 ● Ep.09
Multiomics methods investigating aging process in man's best friend
DNA Genotek speaks with researchers involved in the recently launched Dog Aging Project. The goal of the Dog Aging Project is to understand ... how genes, lifestyle, and environment influence aging and to use that information to help pets and people increase healthspan, the period of life spent free from disease. In this podcast, we speak with Dr. Daniel Promislow from the Dog Aging Project, Dr. Elinor Karlsson from the Darwin's Ark Project and Dr. Janet Patterson-Kane from the Golden Retriever's Lifetime study. see more
Nov 05, 2019 ● Ep.08
The role of the microbiome in childhood determinants of cardiovascular health
The Cardiovascular Risk in Young Finns Study is a prospective longitudinal study initiated in 1980. It is one of the largest follow-up studies into ... cardiovascular risk from childhood to adulthood. The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood. In this podcast, Dr. Katja Pahkala and Dr. Evelina Munukka from the University of Turku, Finland speak about this study, why they recently incorporated gut microbiome samples as part of their research, and what role the gut microbiome could play in cardiovascular health. see more
Sep 17, 2019 ● Ep.07
PREdiCCT: the largest study on predicting IBD disease flare
This week, I interview Dr. Charlie Lees and Lee Murphy, investigators for the PREdiCCt Study (Prognostic effect of environmental ... factors in Crohn’s and Colitis). PREdiCCt is a major study at the University of Edinburgh that is actively recruiting now. This is the first study of its kind and it is directed towards understanding how environmental factors and the gut microorganisms influence Inflammatory Bowel Disease (IBD) flare and recovery. In this podcast, I speak with Chief Investigator Dr. Charlie Lees and Lee Murphy, Genetics Manager at the Edinburgh Clinical Research Facility about the progress to date on the PREdiCCt study, and what they hope to learn. see more
Sep 09, 2019 ● Ep.06
The challenges and opportunities of collecting RNA for human microbiome studies
Jean Macklaim is a Bioinformatician at DNA Genotek who has an extensive history with RNA research. Jean received her PhD in Biochemistry ... and Bachelor of Science in Human Genetics from the University of Western Ontario where she focused on sequencing technologies and bioinformatics methods to understand the structure and function of the microbiome in different disease and environmental conditions. In this podcast, Jean speaks about the challenges and potential RNA has in both the research and clinical fields for human microbiome. see more
Jul 16, 2019 ● Ep.05
The Art of Innovation
An interview with Stephen Tang, President and CEO of OraSure Technologies and its subsidiaries DNA Genotek, CoreBiome and Novosanis. ... Steve spoke about how he fosters a culture of innovation across the entire organization. In the podcast, he discusses how innovation helps the organization respond to change, how developing people and creating opportunities for them makes them more innovative and how he ensures innovation is not a one-time project. UPDATE: On May 12, 2020, CoreBiome rebranded as Diversigen Inc. see more
Jul 07, 2019 ● Ep.04
Saliva as a sample type for genomic applications
This week, I interview Scott Rabuka, Director of the Genomics Program at DNA Genotek for our podcast, Molecules, Microbes and Multiomics. ... Scott joined DNA Genotek in 2008 as the product manager for Oragene and successfully expanded the product into a complete family of solutions for global genomic research and clinical use. He is responsible for the launch of the company's first FDA 510(k) cleared product in 2011 as well as multiple new products designed to address evolving global market opportunities. In this podcast, Scott speaks about saliva as a DNA sample type, who’s using it today and how it compares to other sample types in the field, the clinic and in the lab. see more
Apr 23, 2019 ● Ep.03
Urine as a liquid biopsy for cancer detection
We recently had the opportunity to visit our new sister company, Novosanis, in Antwerp, Belgium, to talk about urine as a sample type. ... Novosanis is dedicated to solving urine sampling challenges through its product Colli-Pee™ - an award-winning device designed to efficiently and hygienically capture first-void urine (the first 20ml of a urine sample). I spoke with their CEO and co-founder, Vanessa Vankerckhoven about the challenges first void urine collection solves for both cancer detection as well as STIs. see more
Mar 27, 2019 ● Ep.02
A look ahead for the microbiome industry
UPDATE: On May 12, 2020, CoreBiome rebranded as Diversigen Inc. We recently introduced listeners of Molecules, microbes and multiomics to ... our sister company, CoreBiome, a privately-held, Minnesota-based microbiome analysis company that accelerates discovery for customers in the pharmaceutical, agricultural, environmental and research communities. We are continuing this story via an interview with CoreBiome co-founder, Dr. Dan Knights. In this new podcast, Dr. Knights speaks to us about why the microbiome is so different from the human genome, what answers microbiome research can provide for wellness and disease that we can’t find elsewhere, and what advice he would give an epidemiologist who is looking to add a microbiome component to their project. see more
Mar 04, 2019 ● Ep.01
The microbiome challenges CoreBiome was built to solve
UPDATE: On May 12, 2020, CoreBiome rebranded as Diversigen Inc. In the podcast, Dr. Dan Knights, co-founder and CEO of CoreBiome discusses ... the problems CoreBiome was built to solve and the challenges surrounding reproducibility in the microbiome field. You’ll learn why he “geeks out” about quality, efficiency, and accuracy and how his team keeps CoreBiome at the forefront of the microbiome industry. Learn more about CoreBiome and what it can do for microbiome researchers and clinicians here. see more