All products / All regions

Description of Services

• Genome characterization and sequencing
• Genotyping assay development and validation
• Gene expression profiling and validation
• Drug efficacy and safety-related analysis
• Biologics evaluation and safety testing
• Data management, analysis and interpretation
• Sample management and biobanking
• Scientific consulting

Description of Services

BioRep S.r.l. is an independent "SERVICE PROVIDER" organization offering biorepository services to public and private research institutes, to the highest standards of quality and safety. In addition to the storage service, BioRep provides Cell Biology, Molecular Biology, Microbiology, Media preparation services developed in ISO9001/2000 certified laboratories (i.e. establishment, maintenance and distribution of cell line cultures as well as DNA derived from these cultures; nucleic acids isolation and distribution, genotyping, sequencing; mycoplasma detection in animal cell cultures; etc).

Applications

• DNA extractions from whole blood (performed manually using the salting-out method).
• DNA extractions from saliva (performed manually using the protocol for 4.0 ml of Oragene®•DNA saliva).
• DNA quantification (and purity evaluation) performed by absorbance using the Nanodrop 1000 spectrophotometer.

Description of Services

DNA and RNA extractions, Realtime PCR analysis, SNP analysis using Sequenoms iPLEX system, expression analysis using the Taqman system. Manual extraction of RNA and DNA. We utilize our proprietary DNA extraction reagents, DNAQuick for DNA extraction from most of the sources. We also utilize Qiagen column protocols for some sample types. For RNA extractions we typically use Tri-reagent method and some times utilize Qiagen column based protocols. We have Standard Operating Protocols (SOPs) for all the different applications.

Description of Services

Molecular Diagnostics

• DNA mutation testing for twenty single gene disorders, Ashkenazi Jewish panel, thrombophilia, mitochondrial DNA disorders.
• Microarray-based comparative genomic hybridization for mental retardation/developmental delay (Agilent Array)
• DNA sequence analysis for disease predisposition genes.

Cytogenetics

• Chromosome and FISH analysis on amniotic fluid, peripheral blood, products of conception, fibroblasts, bone marrow, lymph node and solid tumors.

Biochemical Genetics

• Amino acid and organ acid disorders, mucopolysaccharidoses, defects of carnitine metabolism Diagnostic Microarray Services.
• Affymetrix Gene Expression, SNP analysis and Targeted Genotyping available in our clinical lab at the Center for Applied Genomics www.cag.icph.org
• Proteomic Diagnostics Clinical proteomic assays using MSIA technology which couples antibody affinity capture to mass spectrometry.

Proteomic Diagnostics

• Clinical proteomic assays using MSIA technology which couples antibody affinity capture to mass spectrometry.

Description of Services

CLIA certified services for custom molecular assays. CRL also performs clinical trials, insurance, toxicology and bioanalytical testing.

Description of Services

Expression Analysis provides expression profiling and genotyping services using Affymetrix, Illumina, Luminex and Applied Biosystems' TaqMan® technologies. As the leading provider of microarray services in clinical trials, Expression Analysis offers solutions for challenging specimens, such as blood and FFPE tissues, as well as nucleic acid isolation and data analysis services. The company also performs diagnostic assays in its CLIA and GLP-compliant laboratory.

Lab location and locations served

The Expression Analysis facility is located in Durham, NC. Our services are provided worldwide to a variety of clients including most of the top 10 pharmaceutical companies.

Expression Analysis, Inc.
4324 South Alston Avenue, Suite 101
Durham, NC 27713

Description of Services

In the field of DNA typing, Dr. Van Haeringen Laboratorium b.v. (VHL) has obtained a worldwide reputation over the last 25 years by quality, service and know-how. At the moment VHL offers over 1,000 routine tests for animals, plants and micro-organisms. In collaboration with clients, VHL performs many different projects in various fields. VHL collaborates with clients from different areas of expertise, such as agriculture including veterinarian diagnostics, the pharmaceutical industry, feed & food technology, basic research and organizations related to accompanying animals.

As a DNA Service Laboratory VHL is experienced on several DNA techniques such as Genotyping of SNPs and InDels, MCPC, Sequencing, realtime PCR for pathogen detection, microsatellite analysis, etc. As a technology leader, VHL is used to implement new techniques fast and reliable.

The availability and possibilities of DNA and RNA Technologies has enabled Genetic Services of an entirely new level. Within our scopes, genetic testing is based on a selection of High Throughput platforms, enabling optimal quality and flexibility for a wide spectrum of applications:

• Genotyping Services for SNPs / InDel
• Microsatellite (STR) Genotyping Services
• DNA extraction services
• Bio Banking
• Routine Mutation Analysis
• Real Time Pathogen Detection

Description of Services

Mocite is a company that since 2002 specializes in conducting human genetic research. To ensure that Mocite always delivers high quality research, our priority lays with Quality, Service and Know-how.

To support these three pillars, Mocite is certified and accredited to the highest standards available. By this means Mocite is able to deliver the highest possible quality available in genetic research.

Mocite distinguishes itself from other laboratories by:

• Applying the latest techniques;
• Wide use of different techniques in the field of kinship analysis and genetic characteristics;
• Flexibility in the selection of tests.
• Applications Mocite provides

By combining the latest genetic techniques, Mocite is able to conduct mostly any type of genetic research at low cost. Mocite is experienced in the following technical fields of analysis:

• Biobanking
• Databasing
• DNA Extraction Services
• Genotyping Services for SNPs / InDel
• Kinship Analysis
• Profiling

In addition, all other DNA related projects may be carried out through Mocite as well. These include Sequencing, Next Generation Sequencing and Gene Expression.

Description of Services

OGT was founded in 1995 by the pioneer of microarray technologies, Professor Sir Edwin Southern. The key focus areas of OGT are high throughput microarray and biomarker discovery. OGT also has an extensive range of cytogenetic products and services, including high resolution oligonucleotide arrays, labeling kits and our analysis software, Interpret.

Applications

In our high throughput laboratories we can process arrays for aCGH and CNV studies, ChIP and methylation samples and also gene expression and miRNA profiling. The sample handling and labeling steps are fully automated. Currently most of our projects are run using the Agilent platform.

Description of Services

ProntoLab, the molecular services division of Pronto Diagnostics, provides clinical molecular diagnostics services as well as research services which include:

• Oncogenetic testing - BRCA, FAP, HNPCC - Full sequencing/Point mutations/Deletions/Duplications
• Pharmacogenetic testing - 5FU, Clopidogrel, Irinotecan, Tamoxifen, Warfarin
• Other tests - FMF, TRAPS, THROMBOPHILIADNA Sequencing Fragment Analysis Deletions/Duplications Analysis (MLPA)

Lab location and locations served:

ProntoLab
19A Habarzel St.
Ramat Hachayal, Tel-Aviv 69710, Israel

Description of Services

Clinical molecular diagnostic laboratory (see website for details of services offered)

Lab location:

Molecular Genetics Laboratory
555 University Ave., Roy C. Hill Wing, Rm. 3421
Toronto, ON, Canada
M5G 1X

Description of Services

Source BioScience AUTOGEN™ & Geneservice™ is a contract research service provider and biological resource centre used by research companies and academic institutions worldwide. We are fully CPA, GLP/GCP accredited & most recently we have been awarded CSPro certification. With an archive of more than 16 million DNA samples, over 100,000 specialist and innovative products and a comprehensive portfolio of genomic services supported by the latest platforms and technologies, we are the only company that offers such a unique and wide ranging product and service collection.

Lab location and locations served:

Source BioScience offers genomic services and products worldwide. Our laboratories are based in Cambridge, Dublin, London, Nottingham and Oxford

Description of Services

The UCLA Biomarker Innovations Laboratory (BIL) is a California state licensed and CLIA-certified clinical laboratory founded by Drs. Scott Binder and David Seligson, pathologist-scientists, and is located at one of the world's leading hospitals and academic institutions - the David Geffen School of Medicine at the University of California, Los Angeles (UCLA).

Applications:

The BIL is currently offering the J&J/Veridex CTC (Circulating Tumor Cell Detection in whole blood) assay for monitoring metastatic breast, colon and prostate cancers. EGFRvIII RT PCR Gene Expression -Glioblastoma multiforme (GBM) is the most aggressive brain tumor in adults and remains incurable despite multimodal intensive treatment regimens. EGFRvIII is a truncated extracellular mutant of the EGF receptor (EGFR) commonly found in GBMs that confers enhanced tumorigenic behavior. This assay was developed by the UCLA Neurological research team and the laboratory procedures has been validated by the BIL. The assay includes RNA extraction from 4-8 10 um thickness of tissue sections, reverse transcribe the RNA to cDNA synthesis and followed by SYBR Green Real Time PCR using Roche LightCycler 480.

Lab Location and Locations served:

UCLA Biomarker Innovations Laboratory
710 Westwood Plaza, Room 3235
Los Angeles, CA 90095

Description of Services

Genomic Analysis (Paternity Test, Papillomavirus Genotypification, detection of KRAS, JAK-2 and Factor V mutation).

Lab location and locations served:

Vitagenesis, S.A. de C.V.
Boulevard Puerta del Sol #1005
Monterrey, Nuevo León, México, 64630