- Great service and feed-back from skilled and experienced staff
- Easy and quick to use the products
- Facilitates the data collection
- No complications since it is a non-invasive collection
- Easy to store
- The Oragene kits can be posted to patients
- The product has a high quality"
"The collection of saliva using the Oragene collection kit was easy and fast. The samples are quite stable in the field and while travelling back to the lab, even in the high temperatures of that region (close to 35°C). Furthermore, our analysis on paired Oragene/saliva and blood samples indicates no difference in DNA yield, quality and genotyping results."
Professor Dr. Carlos Menck
University of Sao Paulo
"As a research nurse, one constantly has to balance between the study requirements and the maxim “Do no harm.” Because of the frailty of these patients, Oragene fills the gap in being a non-invasive procedure and has helped my work in terms of recruitment, which should be patient centred and not research centred. The easy application of the Oragene process makes me feel at ease that I have not harmed or caused anyone pain and I can be satisfied that our research has remained patient centred."
Gameda Benefeld, Research Nurse
Division of Human Genetics, University of Cape Town, South Africa
"So far I have collected 38 saliva samples and they are right here with me in my office at room temperature with no extra costs for storage. Thanks to DNA Genotek for this novel innovation that can allow people in low income countries to easily collect and store samples for DNA analysis."
Rispah Torrorey, PhD candidate
University of Moi, Kenya
"Your Oragene/saliva kit is really useful. We are using it in many fields of genome research relating to human diseases – for mutation analysis, exome sequencing and GWAS genotyping – resulting in successful publications."
Dr. Shiro Ikegawa
Laboratory of Bone and Joint Diseases, Center for Integrative Medical Sciences, RIKEN, Tokyo, Japan
"Oragene fullfilled all of our requirements for DNA sampling. It was a completely hassle free approach and we generated high quality and pure DNA for association studies and hence successfully accomplished our research project."
Dr. Toolika Singh, Researcher
Infectious Disease Research Laboratory, Banaras Hindu University
"The Oragene and ORAcollect sample collection kits are providing us with the utmost in flexibility when we require a DNA sample from potential donors who are unable to come to our laboratory. The quality of DNA is more than adequate to meet our needs and has helped us successfully match donors and recipients for life-saving procedures."
Ephraim Gazit, MD, Professor (emeritus) of Pediatrics
"We chose Oragene because the saliva collection kit offers a non‑invasive method to collect DNA. The ambient temperature storage is ideal for us as we had multiple outpatient clinics for DNA collection as well as mail-based collection in Japan. Our use of Oragene has helped us identify the ITPKC gene as one of the responsible genes for Kawasaki disease and we are now trying to evaluate its validity for personalized medicine of KD in a cohort study."
Dr. Akira Hata
Department of Public Health, Chiba University Graduate School of Medicine
"We chose Oragene because the saliva collection kit is very easy to handle and it offers a non-invasive method to collect DNA. The room temperature storage is ideal for us as we had multiple clinics for DNA collection in various locations throughout China. Transporting and storing the DNA saliva samples was easy."
Jianfeng Xu, M.D., Dr. PH.
Wake Forest University Health Sciences
"We chose Oragene primarily because we were working with a cohort of patients aged 2–21 years old and we felt that it was ethically better to be able to offer saliva collection to the parents and guardians of these young people."
John Common, PhD
Institute of Medical Biology, Singapore
"Because the study is non-invasive, it is easy to participate. The DNA that you get from saliva samples is of equal quality to DNA that you get from blood, and unlike blood, these samples will be stable at room temperature for long-term storage."
Susan Kadlubar, PhD
University of Arkansas for Medical Sciences (UAMS) College of Public Health
"The Oragene kits provide an essential supplement to the Generation Scotland project. The easy-to-use kits allow high quality DNA to be collected and isolated. The DNA information generated as a result of Oragene collections along with the other biological material and associated data are now in increasing demand from clinical researchers."
Wellcome Trust Clinical Research Facility, Western General Hospital, Edinburgh, Scotland
"We’re really excited about the switch to saliva testing. Ultimately, this is about saving more lives. Anthony Nolan provides two potentially lifesaving transplants every day, but there is an equal number that we can’t currently help. We urgently need to increase the number of people on our register, and saliva testing will help us do that much more quickly and effectively."
Henny Braund, Chief Executive of Anthony Nolan
"… what’s been very important is [the paediatric hospital in Guatemala] doesn’t have a lot of storage facilities so we have stored samples there at room temperature now for years that provide good quality and quantity DNA.” “We have found in the end Oragene/saliva kits are quite cost effective in terms of the amount and quality of DNA, the stability over time and the ease of extraction. It works very well for us."
Michael Dean, Ph.D.
Senior Investigator and Head of the Human Genetic Section
Laboratory of Experimental Immunology, Cancer and Inflammation Program
Center for Cancer Research, National Cancer Institute, USA
"My experience using the Oragene collection product is only positive. One of the reasons why we decided to use the Oragene kits was due to simplicity of being able to mail the samples to different parts of the country since we collaborate with several clinics. The way we decided to perform the study would not have been possible without the Oragene collection kits."
Dr. Sofia Louca
Department of Dental Medicine, Karolinska Institutet, Sweden
"I am very happy that I started using the Oragene collection kits since they enable my research in every way. I strongly recommend others to start using the Oragene collection kits! It makes your research so much easier! I have listed some of the positive points and advantages of using the Oragene collection kits:
Dr. Sofia Louca
Department of Dental Medicine, Karolinska Institutet, Sweden
"As an academic, we are commonly asked to conduct quality science on a shoestring budget. Fortunately, Oragene/saliva collection kits (DNA Genotek Inc, Ottawa, ON, Canada) make it easy. For more than 3 years I have had the pleasure of using Oragene kits, which provide an incredibly convenient method for collecting and preserving saliva samples for genotyping. Using these kits, we performed nine probe hydrolysis genotyping assays upon 576 saliva samples with a success rate of 99.96%. Moreover, their customer service has been refreshing, efficient, and inspiring. Thanks for providing a stellar product and for backing it up with excellent support."
Chris Stockmann, MSc, CCRP
Senior Clinical Research Coordinator
University of Utah Health Sciences Center
Salt Lake City, UT
"We strive to use the best at GeneCare. Your chemistry is brilliant! We got 260/280 ratios of 1.84 - 1.89. This will change the way we do our collection."
Nico de Villiers (PhD), R&D Manager
GeneCare Molecular Genetics, South Africa
"Oragene•DISCOVER is a unique enabling technology which gives investigators the opportunity to collect samples that would otherwise be unavailable."
Paul Wood, Associate Director
Genomics and Proteomics Core Laboratories, University of Pittsburgh
"It works excellent. I received 150 micrograms DNA from 2ml saliva. Isolated genomic DNA is pure enough for PCR."
University of Colorado Health Sciences Center
"Your kit is magic! Thank you for developing this technology. Now we will have a much easier time sampling our psychiatric patients."
Hacettepe University, Turkey
"The yield was high and in good quality and the procedure itself very friendly and 'fun'."
Rivka Carmi Dean, Health Sciences
Genetic Institute Siroka Medical Center, Ben Gurion University of the Negev
"The main problem for our laboratory has always been DNA collection for out of hospital patients. We were looking for a simple way to collect samples from family members living far away from our center. We have always received blood samples with a lot of problems with the package, the authorizations and the problems were increased when the samples were send from out of Italy patients. With the Oragene•DISCOVER DNA collection kit we found the best solution to our problems. Furthermore, the protocol is very simple to follow and the time for extraction and amplification is greatly reduced with a very good result on DNA amount and quality."
Dr. Raffaella Bloise, MD, Genetic Cousellor
Molecular Cardiology Laboratory, Pavia, Italy
"The collection protocol is very convenient, the extraction is very quick and simple, and the yield is great. Our downstream applications include PCR, restriction enzyme digestion and sequencing.
We have collected numerous family members who were not willing to go for a blood draw, as well as children, elderly patients and overseas relatives. The ease of shipping and self-collection are remarkable. Our lab is very impressed with this timely product."
Ruth McPherson, MD, PhD and Nihan Kavaslar, PhD
Lipoproteins and Atherosclerosis Research Group, University of Ottawa Heart Institute
"I am very impressed with the performance of the Oragene•DISCOVER DNA collection technology. We obtained near perfect DNA human identification profile results under very demanding field conditions and as a bonus, reduced our usual extraction time by a factor of 8 and increased total DNA yields by a factor of 30. I wouldn't hesitate to recommend it enthusiastically."
Dr. R. Ballard
California State University
"The results are amazing. The yield is so surprisingly high, we got 100, 300 and 400 micrograms DNA from these samples. This is a truly great product. I have tried many different chemistries to obtain DNA… and I have not seen a better compromise for yield, purity, time to extract and ease of collection than Oragene•DISCOVER."
Mehdi Keddache, Coordinator
Cincinnati Children's Hospital, DNA Sequencing Services
"By using HOMIM (Human Oral Microbe Identification Microarray), we demonstrated that saliva samples stored in OMNIgene•ORAL were indeed stabilized for at least 3 weeks, even at 37° Celsius. This is outstanding! Consequently, I think OMNIgene•ORAL would be very useful for remote collections alleviating the need for a -80° freezer or, for that matter, any refrigeration to preserve samples. This is an incredible benefit for any investigator who is interested in preserving precious clinical samples, especially for use with molecular analyses of genomic material."
Bruce J. Paster, Ph.D.
Director, Human Microbe Identification Microarray Core
Head, Department of Molecular Genetics
The Forsyth Institute
"The majority of my work revolves around Drug Reaction with Eosinophilia and Systemic Symptoms, or DRESS, a rare and dangerous reaction to a range of common medicines which may be linked to the reactivation of the herpes viruses (HHV-6, HHV-7, CMV, EBV). OMNIgene•ORAL is proving to be an effective tool for the collection and detection of the human herpes virus in oral samples. The DNA collections with OMNIgene•ORAL are easy and painless for the participants, and provide a viable alternative to blood collections. Having the option of using a non-invasive saliva collection device to detect the presence of the herpes virus in patients suffering the drug reaction may provide ways to treat and possibly stop it becoming more severe, or even fatal."
Dr. Vincent Descamps, MD, PhD,
Bichat Claude Bernard Hospital, APHP, Paris
"The OMNIgene•ORAL product has provided very reliable detection of the presence of the human papillomavirus (HPV) in saliva samples. HPV has been strongly associated with certain kinds of head and neck cancer. The ability to detect the HPV virus in a saliva sample provides us with an easy-to-use and non-invasive tool to test our patients. Overall, the testing methods and the OMNIgene•ORAL collection kits have worked extremely well for detection of high risk oral HPV."
Martin J. Corsten, MD FRCSC, Chairman,
Department of Otolaryngology - Head and Neck Surgery, The Ottawa Hospital/University of Ottawa
"SRC GenServe Laboratories™ is pleased to offer Performagene as a sampling option to our clients. The integrated collection and stabilization kit provides us with a highly reliable DNA sample that performs exceptionally well for our livestock genetic tests."
D.A. (Dale) Kelly, P.Ag., Vice President,
Agriculture, Biotechnology and Food, Saskatchewan Research Council
"Performagene as a DNA sampling method allows me to collect from my cattle significantly faster than taking hair samples. Time is critical to every element of farming and Performagene enables easier genetic testing of my herd by decreasing the complexity of sample collection. This DNA collection method is extremely easy and I would recommend to any producer to try this method."
Louis Patenaude of La Ferme Gillette Inc.
"Collecting and extracting high quality DNA from livestock is not easy, yet it is essential as the industry relies more on genomic testing for performance traits and parentage verification. The key to widespread adoption of genomic testing is the availability of a reliable, easy and cost effective means of collecting the sample. Early indications from field trials show the Performagene nasal DNA collection kit offers benefits that address some of these challenges."
Jay Shannon, Breed Improvement Manager
"We chose to use Performagene because we wanted to increase the number of samples collected for our new genetic tests for performance traits and this non-invasive collection method provided adequate DNA quantity and quality. We were also impressed that DNA Genotek was willing to work with us on a custom packaging solution that allowed us to have samples returned via the mail and maximized efficiencies in our laboratory processes. Overall, Performagene met all of our outlined requirements"
Suzanne Harding, Product Services Executive,
Cattle Information Services, Holstein UK
For In Vitro Diagnostic Use.
Oragene•DNA is not available for sale in the United States. Some DNA Genotek products may not be available in all geographic regions.
Full terms and conditions for all DNA Genotek products are available here.
DNA Genotek's sample collection devices and nucleic acid stabilization chemistries are protected by issued and pending patents in numerous countries around the world.
Inside DNA Genotek