- High quality, high quantity DNA
- Equivalent to blood for DNA analysis
- Painless and reliable self or assisted collection
- DNA is stable for years at ambient temperature
- Optimized for both manual sample processing and automated workflows
- Integrated 1D barcode + optional 2D bottom barcode for workflow efficiency
- Proven on targeted and whole genome sequencing
| OGR-675
For assisted collection
Collect superior samples for your genetic analysis
Are you looking for a non-invasive way to collect DNA from patients that cannot or choose not to comply with blood collections? DNA Genotek has developed a product for collecting high quantity and high quality DNA from saliva using absorbent sponges. This method is an all-in-one system for the collection, stabilization and transportation of DNA from saliva.
Overview
Product Benefits
View donor user instructions
Collection method comparison chart
Blood Collection |
Oral Collection |
|||
Attributes |
Venous blood |
Mouthwash |
Buccal swabs |
Oragene•DISCOVER (OGR-675) |
---|---|---|---|---|
Non-invasive collection |
✘ |
✘ |
✔ |
✔ |
Specimen stability at room temperature |
Days |
Weeks |
Days |
Years |
Low bacterial content |
✔ |
✘† (up to 60% bacterial content) |
✘† (up to 90% bacterial content) |
✔ (median 6.8% bacterial content) |
Median DNA yield |
30 µg |
35 µg |
2 µg |
17.3 µg‡ |
Sample size |
1 mL |
10 mL** |
1 swab |
0.75 mL |
Molecular weight |
> 23 kb |
> 23 kb |
< 23 kb |
> 23 kb‡ |
Shipping at ambient temperature |
✘ |
✔ |
✔ |
✔ |
Ideal for non-compliant donors |
✘ |
✘ |
✘ |
✔ |
† Birnboim, H.C., Iwasiow, R.M. and James, C.M.P. (2008). Human genomic DNA content of saliva samples collected with the Oragene self-collection kit. DNA Genotek. PD-WP-011.
‡ Niles, J.O., Rabuka, S., and Iwasiow, R.M. (2010). Non-invasive, assisted collection of high quantity and quality genomic DNA from saliva of young children. DNA Genotek. PD-WP-018.
** Volume of mouthwash used for sample collection.
Oragene•DISCOVER is for research use only, not for use in diagnostic procedures.
Full terms and conditions for all DNA Genotek products are available here.
DNA Genotek's sample collection devices and nucleic acid stabilization chemistries are protected by issued and pending patents in numerous countries around the world.
Literature
This is a truly great product. I have tried many different chemistries to obtain DNA… and I have not seen a better compromise for yield, purity, time to extract and ease of collection than Oragene.
Mehdi Keddache, Coordinator
Cincinnati Children's Hospital, DNA Sequencing Services
DNA from saliva vs. blood
Who wins the cost battle?
Overcoming challenges in DNA sample collection.
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